Risk for acquired retinal detachment in pediatric coloboma may be low

August 23, 2021

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The authors report no relevant financial disclosures.

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The risk of acquired retinal detachment in children with optic nerve coloboma or chorioretinal coloboma may be lower than previously thought, according to one study.

Gil Binenbaum

“Retinal detachment associated with chorioretinal or optic nerve coloboma is quite uncommon during childhood, but does occur,” Corresponding Author Gil Binenbaum, MD, MSCE, chief of ophthalmology at Philadelphia Children’s Hospital, Healio/OSN told. “Children are unlikely to report symptoms, so regular fundus exams to check for a break or detachment make sense.”

The authors conducted a retrospective cross-sectional study in children examined between May 2009 and July 2020 who had an optic nerve coloboma or chorioretinal coloboma in one or both eyes.

The study involved 387 eyes from 258 patients. Two eyes of two children aged 7 years and 14 years had developed retinal detachment, with a retinal detachment rate per eye of 0.52% and a retinal detachment rate per patient of 0.78%.

“The discrepancy between our findings and previous studies is likely due to referral bias and the large number of adults in previous study populations,” the authors wrote.

One limitation of the study was that the prevalence of detachments could be underestimated due to the difficulty of conducting thorough retinal examinations in children, the authors wrote.

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