Pediatric Narcolepsy Scale, How Race Influences Classification of OSA Severity, and More

As reported by NeurologyLive®, the new Pediatric Narcolepsy Severity Scale (NSS-P) was shown to provide adequate psychometric properties and temporal stability in the assessment of more than 150 children and adolescents with type 1 narcolepsy.

Highlighting the potential of a pediatric population scale, NSS-P was reformulated from the original NSS and yielded self-reported sleepiness, insomnia, and depressive symptoms in school-aged children and adolescents diagnosed at 3 reference centers for narcolepsy in the United States. France.

The scale may be particularly unreliable in children under 10 years of age, as young children may have difficulty recognizing and quantifying symptoms such as cataplexy. Symptoms associated with NT1, including fatigue, brain fog, and autonomous behavior were also not evaluated by the NSS-P questionnaire.

Race/Ethnicity May Affect the Classification of Obstructive Sleep Apnea

Differences in sleep phenotypes characteristic of moderate to severe obstructive sleep apnea (OSA) between Caucasian and Hispanic/Latino patients may justify the incorporation of new classification classes in these populations, according to research findings published in Sleep.

As reported by NeurologyLive®, data from the Sleep Apnea Global Interdisciplinary Consortium on primarily non-Hispanic White and Asian participants recommended the classification of OSA into 5 symptom classes. Conversely, analysis of the Hispanic Community Health Study/Study of Latinos on Hispanic/Latino patients identified 3 phenotypes for categorization, including minimally symptomatic (47.7%), excessive sleepiness (37.1%) and disturbed sleep (15.2% ).

In addition, differences in comorbidity profiles were found to differ by the classified phenotype, with patients with the excessive sleepiness phenotype more prone to obstructive pulmonary disease and those of the disturbed sleep phenotype more likely to self-report cerebrovascular disease and/or cardiovascular disease. attack.

Assessment of the state of sleep research, progress in unmet needs

In an interview by NeurologyLive®, Raman Malhotra, MD, associate professor of neurology, Washington University in St. Louis, and president, American Academy of Sleep Medicine (AASM), spoke about the current state of sleep care and how unmet needs impact future research .

With AASM’s recent position statement confirming sleep as an essential part of health, Malhotra said that major health problems that are prominent in the United States are affected by sleep health, including obesity, ischemic risk and dementia. However, he noted that further research into how sleep plays a mediating role in the risk of neurological disorders is needed, as the knowledge about the association is still in its infancy.

In addition, he said finding a cost-effective approach to better measure sleep across multiple nights would help improve the representative data on sleep quality and duration, and then underscore the impact of these issues on overall health.

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